CD35, also known as complement receptor type 1, is a type I membrane glycoprotein from complement activation (RCA) family. It is expressed by glomerular podocytes, follicular dendritic cells, erythrocytes, and leukocytes (B cells, subset of T cells, monocytes, macrophages, neutrophils, and eosinophils). Abnormal expression of this protein has been associated with sarcoidosis, gallbladder carcinomas, mesangiocapillary glomerulonephritis, and systemic lupus erythematosus.
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1219_CD35 (SP191).pdf (49.5Kb)