ZytoLight ® SPEC ALK/2q11 Dual Color Probe

 Probe Description: The SPEC ALK/2q11 Dual Color Probe is a mixture of a green fluorochrome direct labeled SPEC ALK probe hybridizing to the human ALK gene in the chromosomal region 2p23.1-p23.2 and an orange fluorochrome direct labeled SPEC 2q11 probe. The SPEC 2q11 probe is specific for the AFF3 (AF4/FMR2 family, member 3) gene region in 2q11.2. Due to crosshybridizations of chromosome 2 alpha satellites to other centromeric regions, probes specific for 2q11 are frequently used for chromosome 2 copy number detection.