ZytoLight ® SPEC MAML2 Dual Color Break Apart Probe

The ZytoLight ® SPEC MAML2 Dual Color Break Apart Probe is designed to detect the translocation t(11;19)(q21;p13.1) specific for mucoepidermoid carcinomas. The mucoepidermoid carcinoma is the most common malignant tumor of the salivary gland. With about 30-50% of all cases, the translocation t(11;19) (q21;p13.1) is the most frequent chromosomal aberration in mucoepidermoid carcinomas. In some cases the t(11;19) is the sole chromosomal anomaly and in other cases the t(11;19) was found either as a more complex translocation involving other chromosomes or together with other abnormalities.