The ZytoLight SPEC BCL2 Dual Color Break Apart Probe is designed to detect translocations involving the chromosomal region 18q21.33 harboring the BCL2 gene. Translocations involving the BCL2 gene are commonly identified in B-cell lymphomas. In particular, the translocation t(14;18)(q32.3;q21.3) has been identified in about 80% of follicular lymphoma.
